As metformin levels were usually not determined in cases in which alternative causes of LA had been identified, coincident metformin accumulation may have been missed.
HBV and HCV chronic infection was determined in cases and in referents by serologic markers [HBV surface antigen (HbsAg) and anti-HCV antibodies].
Genotype and MAF were determined in cases and controls, both of French Canadian origin, for all coding variants as well as the intronic variants showing a MAF ≥ 5%.
Interestingly, the highest effect was determined in case of DLD-1 cell line indicating the independence of p53 status.
Furthermore, the influence of combinations of poisons using Design of Experiments (DOE) has been determined in case of impregnated catalysts.
The complexes as well as the ligands were characterized by spectroscopic methods as well as the solid state structures determined in case of 2a, 3a and complex 5.
However, S s can not be determined in case 4, i.e., in normalized loading curves by Heath et al. (1990).
Different degradation process was determined in case of less random PLACL 75 : 25 and more random PLACL 75 : 25.
An interim analysis was planned after the enrollment of 40 patients, and a stopping rule was determined in case of major morbidity being detected in this phase.
This point should be defined in a general manner by guidelines and policies and cannot be determined in case studies involving patients or employees.
