Sentence examples for determining gene expression changes from inspiring English sources
This result emphasizes the limitations of peripheral blood studies in determining gene expression changes in diseased target tissues.> Pathways associated with dendritic cells and antigen presentation were significantly upregulated (Table 3).
For determining gene expression changes greater than or less than 2-fold, data sets were filtered for genes containing at least two significant values out of four array sets.
We have used histological evaluation and molecular profiling to determine gene expression changes in 23 human patients undergoing surgical procedures for the treatment of chronic tendinopathy.
Finally, since the output of a given signaling pathway (for example, the Wnt and Notch pathways) will a priori be cell context-dependent, studies to determine gene expression changes ideally should be performed on defined cell subpopulations.
This was performed at a global level using genome-wide microarrays to determine gene expression changes and short 1D-gel separation followed by MS/MS analysis on a LC-coupled Orbitrap mass spectrometer to determine quantitative changes in apoplastic protein levels.
Interestingly, data already published from our laboratory has used oligonucleotide microarrays to determine gene expression changes in either resistant (BALB/c) or susceptible (AKR) mice infected with the E isolate of T. muris at 19 or 60 days post infection (p.i).
The edgeR statistical package was used to determine gene expression fold changes using the current Genbank gene annotation information for C. jejuni NCTC11168 [ 19, 20].
Interestingly, we found a completely different expression pattern for B6, the only orally-infected sample, compared to the intracranially infected animals, except for a couple of genes (AKR1C1, NCAM1), suggesting that the route of infection might play a role in determining the gene expression changes (Additional file 6).
