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The CHAID dendrogram illustrated the relative importance of significant independent variables in determining combination use; the most important variables in predicting combination use were certified care need level, living arrangements, cognitive function, and need for medical procedures.
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Some studies seeking to identify clinical stages in bipolar disorder by determining combinations of predictive factors have found that there was no difference in mean illness duration between groups identified with 'good' versus 'poor' outcomes (Reinares et al. 2013).
Once the mechanism of resistance has been determined, combination therapies could potentially allow for the direct targeting of resistant mechanisms.
Table 1 presents the four paired scenarios (1A 1B, 2A:2B, 3A 3B and 4A 4B) consisting of a randomly determined combination of three attributes, each with two levels.
To determine whether various 267/drug combinations had resulted in synergistic, antagonist, or additive effects, the median effect principle (MEP) method of Chou and Talalay was used to determine combination index (CI) values [ 26, 33, 34].
The brain has been created to ingest and compute billions of data points in specific areas such as health and material science, to help scientists better determine combinations that might finally solve persistently difficult problems in fields like medicine.
Local opinion expressed via Congressional delegations determines combinations for adjacent areas with an employment interchange of at least 15 but less than 25.
Utilizing random forests, an ensemble machine learning approach, we determined combinations of significantly associated miRs that contributed to the expression fold change of the underlying targets.
From these two EC50 values we were able to construct an isobologram and theoretically determine combinations of low concentrations of both drugs that would potentially have a supra-additive effect (synergism) (see Methods).
Boolean gating was used to determine combinations of antigen-specific cytokine-producing cells.
We tested all possible combinations of segment ends to determine combinations that produced PCR products when using whole genomic DNA as a template.
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