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Whereas a significant downregulation of Mcl-1 and Bcl-xL survival proteins was also observed in U266 cells following 4EGI-1 thistment, this cell line did not undergo apoptosis, which indicates that the reduction in expression of these anti-apoptotic proteins was not sufficient for determining a commitment to cell death.
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An organization may have a policy that determines a commitment to use a particular methodology.
This chapter examines the issue of dispatch efficiency raised by the design of markets based on central versus self-commitment by determining a set of "competitive benchmarks" for the two market designs.
Provide specific delivery dates to customers. 1 common factor that determines a buyer's commitment to purchasing from you is your ability to deliver within an allotted time period, especially during the holiday calendar count down.
With the right strategies and a determined commitment to a united Ireland can happen.
"My sense... is that he is a person who sizes up opportunities and situations very quickly [and] when he determines to make a commitment to do something, he does it and doesn't look back," Kirby said.
It is impossible to determine what such a commitment might have done to improve race relations over the nearly one-half a century since the Kerner Commission presented its "call to action".
The size of the study was determined based upon a commitment to the US Food and Drug Administration FDAA) to provide safety and efficacy data for adalimumab when used in 2 to <4 year old patients with JIA, and, in accordance with the FDA, the proposed sample size for this study was approximately 30 patients.
Epigenetic variation, which could be a function of numerous factors, including age and environmental conditions, has been shown to characterize stem cells and to play an important role in determining cell commitment and plasticity [62] [64].
The transcription factor PR domain containing 16 (PRDM16) is a critical switch factor in determining the commitment of mouse Myf5+ precursors to brown adipocytes versus myogenic cells (Jimenez-Preitner et al., 2011; Kajimura et al., 2009).
Another objection to the above account of determining ontological commitment goes further and questions the use of a canonical notation, and of formal tools in general.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com