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As the molecular shape determines the functions of a molecule, understanding molecular shapes is important for understanding the biological system of life and thus for designing drugs.
The transcriptome, the contents of mRNA, determines the functions of a cell.
More importantly, the fact that aPPD's pharmacological functions correlate with activity of raft-associated Akt but not that in the total PM further emphasizes the notion that only raft-associated Akt determines the functions of its signaling.
More importantly, the fact that tumor-cell survival solely correlate with Akt activity of lipid rafts instead of nonraft compartments in the PM further emphasizes the notion that only raft-associated Akt determines the functions of its signaling.
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Resolving Ecosystem Complexity develops a framework for anticipating the ways environmental context determines the functioning of ecosystems.
It is system dynamics that determines the function of cells, tissues and organisms.
It is increasingly recognized that it is dynamics of the systems that determines the function of cells, tissues and organisms.
The discovery that splenectomy inactivates CAP strongly supports that spleen determines the function of CAP [ 9].
HIF-1α is a unique O2-regulated subunit that determines the function of HIF-1.
Proteins are generally composed of several domains and the combination of the domains determines the function of the protein.
According to this model, the fine balance between the TA and ΔN isotypes determines the function of p63 proteins.
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