Whereas a significant downregulation of Mcl-1 and Bcl-xL survival proteins was also observed in U266 cells following 4EGI-1 thistment, this cell line did not undergo apoptosis, which indicates that the reduction in expression of these anti-apoptotic proteins was not sufficient for determining a commitment to cell death.
Provide specific delivery dates to customers. 1 common factor that determines a buyer's commitment to purchasing from you is your ability to deliver within an allotted time period, especially during the holiday calendar count down.
Giving employees permission to say no to excessive work assignments is a way to relieve such stress and increase their positive engagement in the workplace, which ultimately determines an employee's satisfaction, commitment, and enthusiasm for their work.
"My sense... is that he is a person who sizes up opportunities and situations very quickly [and] when he determines to make a commitment to do something, he does it and doesn't look back," Kirby said.
This chapter examines the issue of dispatch efficiency raised by the design of markets based on central versus self-commitment by determining a set of "competitive benchmarks" for the two market designs.
With the right strategies and a determined commitment to a united Ireland can happen.
It is impossible to determine what such a commitment might have done to improve race relations over the nearly one-half a century since the Kerner Commission presented its "call to action".
The size of the study was determined based upon a commitment to the US Food and Drug Administration FDAA) to provide safety and efficacy data for adalimumab when used in 2 to <4 year old patients with JIA, and, in accordance with the FDA, the proposed sample size for this study was approximately 30 patients.
Corporate culture determines individuals' commitment, satisfaction, productivity and longevity with an organization [ 21] because individuals tend to select organizations with which their own values are aligned [ 22].
Patient safety culture (PSC) is defined as 'the product of individual and group values, attitudes, perceptions, competencies and patterns of behaviour that determines the commitment to, and the style and proficiency of, an organization's health and safety management' [ 4].
