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As the catalytic function of Set2 is responsible for providing resistance to DSBs (Fig. 1) and full activation of DDR (Fig. 3), we next determined whether the levels of H3K36me change after induction of DSB.
On the other hand, we determined whether the levels of certain candidate proteins were affected by the mutation since degradation is a common hallmark of Hsp90 clients upon Hsp90 inhibition.
It remains to be determined whether the levels of cC5aR change in a similar manner in humans.
We then determined whether the levels of GRN in plasma could be used to distinguish GRN loss-of-function mutation carriers from non- GRN carriers in our FTLD series.
We first determined whether the levels of 3′-external transcribed sequence (ETS) transcripts were influenced by Grc3 using a strain in which GRC3 is under the control of a regulatable promoter (Tet Off).
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In the present study, we determined whether the level of cortical excitability changes with the time interval from the last migraine attack, thereby accounting for the inconsistencies in previous reports.
We thus determined whether the level of pCREB in the nucleus of APP mice (effective pCREB) was affected by xamoterol.
We also determined whether the level of neutrophil infiltration into FasL-positive tumour nests was affected by the presence or absence of tumour-expressed TGF- β1.
If two or more drugs were approved for treating the same orphan disease, we determined whether the level of effectiveness was related to their annual costs.
The purpose of this study was to determine whether the levels of cystatin C and beta-2 microglobulin (B2M) are altered during the second trimester in the plasma of women who subsequently develop preeclampsia.
We performed a pilot study to determine whether the levels and activity of MMP-2 and MMP-9 are elevated in the sera and saliva of patients with VE disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com