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Thus we determined their effects on the interaction with biological environments.
To probe the structural role of the free cysteine at position 83 in FGF-1, we constructed Ala, Ser, Thr, Val, and Ile mutations and determined their effects on structure and stability.
Study 1 was designed to quantitatively manipulate the plasma concentrations of uric acid using hemin and allopurinol while study 2 determined their effects on skin pentosidine, the shear force value of Pectoralis major muscle, plasma glucose, body weight and chemiluminescence monitored oxidative stress in broiler chickens.
In this study, we acutely administered systemically sazetidine-A and two other selective α4β2 nicotinic receptor-desensitizing agents, VMY-2-95 YL-2-203 YL-2-203 YL-2-203ltofemale Sprague-Dawleyoungs adultetermined their efemale on IV Sprague-Dawleyation of cocaine and methamphetamine.
Taken together, these results suggest that the size and surface characteristics of the silica particles determined their effects on CYP3A4 activity and that it may be possible to develop silica particles that do not have undesirable effects on metabolic enzymes by altering their size and surface characteristics.
To ensure that MEK inhibitors-enhanced HCV replication was not due to a non-specific off-target effect of these drugs and to test whether the responsible effectors were downstream of MEK, we took advantage of the dominant negative strategy to inactivate the constitutive MEK-1, ERK-1, and ERK-2 activity and determined their effects on HCV replication.
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Then, we have determined their effect on MS- and GPCR-related gene expression profiles using custom arrays along with FTY720 treatment at non-toxic doses (EC10).
We expressed rabbit recombinant (r cTnT(1) and rcTnT(4) in Spodoptera frugiperda cells and determined their effect on calcium binding to TnC in solution and on the calcium sensitivity of myofilaments in skinned rabbit ventricular fibers in vitro.
Using microarray analysis and cell viability assays, we evaluated different transfection reagents to determine their effects on gene expression profiles.
qRT-PCR analyses were conducted to determine their effects on dopamine-related genes in the striatum.
Various geometric parameters are investigated to determine their effects on the impact resistance of laminated glass.
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