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This check step conclusion determined the need of matching for further analyses to neutralize the confounding factors.
Finally, we determined the need of Pkh for the proper Hsf1 and Msn2/4-driven transcriptional response to heat stress, but not for the down-regulation of genes coding for ribosomal proteins under these conditions.
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Translocation rates were assessed under static and shaken conditions to determine the need of a simple dynamic experimental set up, when investigating placental translocation in vitro, since horizontal shaking is often performed to mimic in vivo exposure.
A correct and precise clinical history and examination will determine the need of further examinations.
To determine the need of nestin and vimentin for GR anchoring we analyzed cell lines varying in IF-protein composition.
The characteristic of chronicity determines the need of new active disease modifying drugs.
Such studies would help clinicians to determine the need of specific cartilage treatments.
In patients presenting with acute liver failure (ALF) prediction of prognosis is vital to determine the need of transplantation.
Molecular profiles have improved our ability to determine the need of chemotherapy for those individuals who are deemed high-risk.
The clinical phenotype, rather than the age, represents the main variable able to determine the need of more frequent administrations of the drug at higher dosage.
In the drug development process the outcome of physiologically based pharmacokinetic (PBPK) simulations are used to determine the need of clinical drug-drug interactions studies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com