Sentence examples for determined that induction of from inspiring English sources

We determined that induction of FRG1-FLAG in iC2C12-FRG1 myoblasts has a negative effect on their proliferation rate, as shown by the increased doubling time when grown in doxycycline (Figure 4A).

Our preclinical studies determined that induction of ER stress and the BH3-only pro-apoptotic gene NOXA are key mediators of Reolysin-induced apoptosis [ 9, 13].

Since lytic granules contain cytolytic proteins, we determined that the induction of microtubule destabilization occurred prior to signs of apoptosis.

The authors determined that the induction of HSP25/27 expression levels and the change in the pattern of expression were hallmarks of the response of the allograft to CAN-related hypoxia and oxidative stress.

Finally, in mammalian cell lines, we recently determined that the induction of autophagy triggered by nutrient starvation occurred concomitantly with a remodeling of the proteins involved in ER Ca2+ homeostasis and dynamics, thereby sensitizing multiple Ca2+-handling mechanisms.

Further exploration determined that transcriptional induction of SNAI2 (Slug) was essential for cyclin D1b-mediated proliferative and invasive properties, implicating Slug as a critical driver of disease progression.

In the present study, we determined that low dose OVA/CpG + MP circumvented induction of oral tolerance with comparable serum anti-OVA antibodies relative to the animals gavaged with 0.05 mg OVA/CpG + MP relative to the i.p. control animals.

In previous extensive kinetic experiments, we determined that maximum levels of induction of CYP1A mRNA in tomcod occurred at these times after treatment with these chemicals (Courtenay et al. 1999).

In addition to these inhibitors, we also determined that FGF-mediated induction of DUSP6/ MKP- 3 was unaffected by inhibition of either the TOR (target of rapamycin) pathway using rapamycin (100 nM) or phospholipase C activity using U-73122 (4 μM) (results not shown).

In addition, we determined that TGF-β1 induction of a Smad responsive promoter is reduced by about 50% in HKc/DR, compared to HKc/HPV16.

These controversial reports suggested that downregulation of the anti-apoptosis protein Bcl-2 alone does not necessarily result in apoptosis, especially considering the fact that induction of apoptosis is determined by a balance of multiple pro-apoptosis proteins and anti-apoptosis proteins [ 38].