Das et al. (1985) observed in (SKH hairless) mouse skin low, but significant epoxide hydrolase activities (0.11 ± 0.01 nmol BP-4,5-dihydrodiol formed/min/mg microsomal protein) (compared with 2.35 ± 0.18 in the liver as determined in the same mice in the same study).
Das et al. (1985) observed in (SKH hairless) mouse skin low, but significant AHH activity (10.56 ± 0.12 pmol 3-hydroxy-BP formed/min/mg microsomal protein) and ECOD (12.39 ± 0.10 pmol 7-hydroxycoumarin formed/min/mg microsomal protein) activities (compared with 625.50 ± 5.63 and 1,198.6 ± 37.8, respectively, in the liver as determined in the same mice in the same study).
Das et al. (1985) observed in (SKH hairless) mouse skin low, but significant GST activity (53.83 ± 0.91 nmol CDNB GSH conjugate formed/min/mg cytosolic protein) (compared with 1,506 ± 12 in the liver as determined in the same mice in the same study).
(F ) Lung MLI was determined in the same group of mice.
mRNA expression in SFM was determined in the same way.
The boundary correction Y was determined in the same manner.
Tracer uptake in the proximal aorta and arch of each mouse, determined as %ID from scans, plotted vs. %ID/g (well counter) determined for the same anatomical aortic section in the same mouse correlated significantly, (r = 0.75, P = 0.0017) (Figure 4C).
Specifically, regression analysis was used to determine if log (pan-HSV-2 IgG level) in an individual mouse was predictive of log (reduction in HSV-2 MS shedding) observed in the same mouse 24 hours after vaginal challenge (Fig. 5D).
The percent of mosaicism varies from mouse to mouse, and among tissues in the same mouse.
For the SPECT studies of In-minigastrin and In-exendin (after which the mice were killed), the correlation between renal uptake measured on the SPECT images and uptake in the same mice measured ex vivo was determined.
