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To simulate the transfection of MITF, the MITF production rate was elevated from 1 to 7. To simulate the transfection of PIAS3, the PIAS3 production rate was elevated from 1.262 to 4. The amount of RSK1 is not dynamically determined in the model, and thus the transfection of this product is approximated with an elevation of the static amount from 500 to 5000.
To simulate transfection of MITF, the MITF production rate was elevated from 1 to 7. The amount of RSK1 is not dynamically determined in the model, and thus the transfection of this product is approximated with an elevation of the static amount from 500 to 5000.
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The effect of studied NPs on morphometric growth parameters of pleistophyte was determined in the model experiment measuring plant weight and number of plants, leaves, and roots per plant and newly formed plants.
These differences may be due to differences in healthcare facilities available i.e. hospital location and access, or differences in population demographics i.e. high Asian ethnicity in Leicester city or differences in how patient characteristics were determined in the model i.e. age, ethnicity and deprivation.
The values for K and λ were determined in the model calibration procedure described below.
How the division plane is located is determined in the model by a division rule.
Benefits to society were based on extra years of productivity, as measured by GNI per capita, resulting from the quality adjusted life-years (QALYs) saved with the use of trastuzumab as determined in the models by Kurian, Liberato and Garrison.
(See Fig. 1; Wymer (1993) and Donaghy et al. (2007) provide details of the estimation algorithm).8 In estimating each block, some variables that were, in theory, endogenously determined in the complete model (and were treated endogenously in another block) were of necessity treated as exogenous.
The false discovery rate (FDR) of classifying breast cancer subtypes was determined in the best models, and we selected those significant at the FDR <0.2 level.
This suggests that the true probe geometry is larger than determined from the model, and that, in turn, the electrode is recessed.
Unfortunately, detailed measurements to determine the deformation response of the anchors were not taken during the experiments so the values used were obtained by calibration based on agreement between the peak load determined in the finite element models and the peak force applied experimentally.
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