Adverse events were registered for type of complication, severity (i.e. requiring re-intervention or not) and moment of onset, up to 6 weeks after discharge (i.e. marking the legitimate adverse event reporting period), according to the definitions and regulations as determined by the Guideline Adverse Events of the Dutch Society of Obstetricians and Gynaecologists [14].
Hypertension diagnosis showed substantial agreement with the reference standard as determined by the guideline (κ = 0.778), the sensitivity was 85.22%, the specificity 96.95%, the positive predictive value 85.24%, and the negative predictive value was 96.95%.
Adverse events were registered for type of complication, severity (i.e. requiring re-operation or not) and moment of onset, up to 6 weeks after discharge (i.e. marking the legitimate adverse event reporting period), according to the definitions and regulations as determined by the Guideline Adverse Events of the Dutch Society of Obstetricians and Gynaecologists [ 39].
The agreement for diabetes mellitus with the reference standard as determined by the guideline was almost perfect (κ = 0.990), with a sensitivity of 99.53%, a specificity of 99.49%, a positive predictive value of 91.23% and a negative predictive value of 99.98%.
The number of liver transplants, however, is determined by the clinical guidelines and availability of donors.
Interestingly, the last two patients (patients 5 and 6) whose PEEP was also determined by the ARDSnet guidelines were found to have a positive EETP pressure of 10.2 and 7.4 cm H2O, respectively.
The modes of distribution and capturing responses (that is, web vs. paper based) were determined by the local guideline implementation team.
b Euthanasia appropriate for each species was determined by using the guidelines reported by the Canadian Council on Animal Care [ 38], and the American Veterinary Medical Association [ 39], respectively.
