Sentence examples for determined antagonists from inspiring English sources

Still, even Mr. McCain's most determined antagonists say the animosity among conservative leaders does not necessarily extend deep into the rank and file, where not many remember the details of Mr. McCain's views on campaign finance or judicial nomination procedures.

Based upon previously determined antagonists for chemokines, we devised a set of screens that mimicked the behaviour of a low-level pharmacophore: it specified that molecules should have molecular weight >500, contain at least two 5- or 6- membered aromatic rings, and at least one nitrogen atom.

But the message of the blazon had not been lost on Cecil, Mary's "most vehement and determined antagonist".

This will determine antagonists, weapons, and even dialogue, so it is very important.

More studies are needed to determine if antagonists are better radiotracers for sstr2 breast cancer imaging than agonists, particularly in other breast cancer xenografts, and ultimately in luminal breast cancer patients.

To determine if antagonists for the wildtype 5-HT4 receptor also activate the human 5-HT4-D100A mutestedwe tested a variety of compounds.

Sasmal et al. investigated the potential anti-obesity activity of quinazoline derivatives, which were determined as MCHR1 antagonists [18].

We also determined whether TNF antagonists added in vitro to blood cells alter their activation by mycobacterial antigens.

It remains to be determined how ETA antagonists cause fluid retention, however the current studies suggest that blockade of nephron ETA may pay a role.

Studies carried out at the cellular levels and in animal pain models were in concert with previously noted analgesic actions of calmodulin-antagonists determined in vivo [32], but we gave here new evidence that calmodulin antagonists can directly block ion channel function of TRPV1.

The logarithm of the octanol-water partition coefficient of the A3R antagonists were determined at pH 7.4 by high-performance liquid chromatography (HPLC -based assay (HPLC -based) modified from Donovassayd Pescatore [41].