Sentence examples for determined antagonist from inspiring English sources

But the message of the blazon had not been lost on Cecil, Mary's "most vehement and determined antagonist".

Still, even Mr. McCain's most determined antagonists say the animosity among conservative leaders does not necessarily extend deep into the rank and file, where not many remember the details of Mr. McCain's views on campaign finance or judicial nomination procedures.

Based upon previously determined antagonists for chemokines, we devised a set of screens that mimicked the behaviour of a low-level pharmacophore: it specified that molecules should have molecular weight >500, contain at least two 5- or 6- membered aromatic rings, and at least one nitrogen atom.

This will determine antagonists, weapons, and even dialogue, so it is very important.

The EC50 determined at each antagonist dose (A') was normalised to the EC50 determined in the absence of antagonist (A) as [Log10 ((A′/A) − 1)] to derive the fold-shift in agonist EC50 at each antagonist dose.

It is of significance therefore, that we have determined that the antagonist activity of ICI and its ability to induce ERα degradation are not coupled processes.

More studies are needed to determine if antagonists are better radiotracers for sstr2 breast cancer imaging than agonists, particularly in other breast cancer xenografts, and ultimately in luminal breast cancer patients.

To determine if antagonists for the wildtype 5-HT4 receptor also activate the human 5-HT4-D100A mutestedwe tested a variety of compounds.

Studies carried out at the cellular levels and in animal pain models were in concert with previously noted analgesic actions of calmodulin-antagonists determined in vivo [32], but we gave here new evidence that calmodulin antagonists can directly block ion channel function of TRPV1.

Sasmal et al. investigated the potential anti-obesity activity of quinazoline derivatives, which were determined as MCHR1 antagonists [18].

We also determined whether TNF antagonists added in vitro to blood cells alter their activation by mycobacterial antigens.