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To determine whether the unique upstream regions in each 5' leader can also internally initiate translation, these regions were inserted into dicistronic RNA constructs and transfected into C6 cells.
To begin, we evaluated the contribution of the exposure time and X-ray energies associated with the beam to the cell death process and thus, determine whether the unique factor that influences the fate of the cell is the total amount of energy delivered to the system.
Thus, it will be interesting to determine whether the unique domain arrangement with BoNT/E underlies its ability to oligomerize in a pH-independent manner upon binding GT1b.
Further studies are needed to determine whether the unique phenotype demonstrated by aASCs is indeed related to the physiological role of their progenitors in fat tissue.
To determine whether the unique or intersecting gene lists associated with each mutant allele displayed enrichment in known biological processes or curated gene signatures, we cross-referenced each to the molecular signatures database [MSigDB (www.broadinstitute.org/gsea/msigdb/)].
To determine whether the unique chemical and physical properties of new nanoparticles result in specific toxicologic properties, the nanotechnology community needs new ways of evaluating hazard and ultimately assessing risk (Nel et al. 2006).
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It remains to be determined whether the unique ability of VLDLR to bind the Pafah1b complex affects postnatal brain function in addition to neuronal positioning during embryogenesis.
These studies are essential in determining whether the unique observed effects of GLP-1R agonists on cardiovascular function depend on the model systems studied, or are a relevant clinical observation.
In order to determine whether this unique mitochondrial redundancy extends to the functional level, we characterized seven mitochondrial genes of D. baltica: five from the endosymbiont (cox1, cox2, cox3, cob, and LSUrRNA) and two from the host (cox1 and cob), and confirmed that cox2 and LSUrRNA from the endosymbiont and cox1 from the host are also present in K. foliaceum.
In order to determine whether these unique cells, indeed, had their origins in the bone marrow, experimental murine models of sex-mismatched bone marrow chimera mice were utilized.
Because the depth of coverage across the genome was different between lines, it was difficult to specifically determine whether the SNPs are unique to any particular genotype.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com