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Additional analyses will determine whether the pathway via reduction of alcohol consumption was indeed crucial to the differences in adherence.
Here, we have analysed these replication licensing factors (RLFs) to determine whether the pathway becomes deregulated during mammary carcinogenesis, and have assessed their potential value as prognostic markers.
We then used the GbeSu(H -lacZ transgene to determine wH -lacZtransgeneay is affectodetermine detected a delayed and reduced expression of N reporter activity in Mad clones (supplementary material Fig. S4D), indicating that TGFβ signalling is required for proper N activity in the flattening StC.
To determine whether the pathway analysis was complementary at the protein level, proteins were extracted from heart tissue, analyzed by iTRAQ (Additional file 11: Table S9; data includes proteins with at least a 1.3-fold change in expression when compared to time-matched controls), and compared with gene expression at all three time points.
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This makes Gal1p a crucial enzyme in the Leloir pathway of galactose uptake, as it determines whether the pathway is switched on or not.
The proportion of 53BP1 or BRCA1 at DSB sites determines whether the repair pathway is NHEJ or HR.
The Bcl-2 family comprises both proapoptotic and antiapoptotic proteins, depending on their BH domain composition, and it is the balance between both types of proteins that determines whether the mitochondrial pathway to apoptosis is activated [ 80].
To evaluate the mechanisms of action in two successful geriatric clinical trials that tested multicomponent physical conditioning programs and to determine whether the pathways for overall benefit were through improvement in physical ability and/or self-confidence.
To determine whether the pathway-based circular permutation approach detects more effects and can explain more variation within a trait than the traditional single-marker approach; the arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway was selected to investigate how much variance was explained by the SNPs within the pathway.
We assessed the expression of molecules within each of the UPR signaling pathways to determine whether the pathways were activated.
To determine whether the pathways converged onto individual granule cells, Huang et al. used a second transgenic mouse line, the TCGO line, which expresses a yellow reporter in a random subset of granule cells.
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