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These grades are used to determine whether the detected event is from a real photon or from a background event, such as a cosmic ray hit.
Fitness of the SBW25 allelic replacement constructs was estimated relative to SBW25-lacZ in glucose, succinate and mannitol environments to determine whether the detected fitness improvements were glucose specific.
But one challenge is that sequencing tools can't determine whether the detected DNA came from a living or dead organism.
What is even more important is to determine whether the detected decrements in H3K27me3 peaks reflected true enzymatic demethylation events.
To determine whether the detected CXCR4 protein was functional, we analysed its ability to induce changes in intracellular calcium levels after rhCXCL12α stimulation.
These isolates represented the isolate diversity in California, and they were used to determine whether the detected QTL showed isolate-specificity.
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This method determines whether the instrument detects differences between groups and is based on testing the hypothesis that time and intervention, both surgical and analgesic, should alter the pain scores [ 16].
However, none of these studies determined whether the detected CYPs were preferentially expressed in the CD34+ cells, and the expression of the other human CYPs in HSPCs has not been examined.
Since the retention times of the spiked compounds are known, it can be determined whether the detected peak originates from a spiked compound: Only if the previously established retention time of one spiked compound falls within this time window will the detected peak be considered a potential spike.
Therefore, it remains to be determined whether the detected differences in nociceptive responses is due to the absence of mast cells per se or a yet unknown change in the responsiveness of sensory neurons due to a congenital lack of the c-kit receptor.
The construct validity was also assessed using the known-group method, a kind of validity which determines whether the instrument is able to detect differences between groups [ 19, 27].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com