Neurofilament heavy and light chain levels and other validated biomarkers, such as anti-aquaporin 4 autoantibodies, need to be explored in longitudinal studies to determine their relation to structural measures of the visual pathways and prognostic value for neurodegeneration-related visual impairment in patients with optic neuritis and multiple sclerosis.
Another limitation may be not having taken into account the degree of severity or admission diagnoses to determine their relation with cocaine use.
More functional studies of these genes are needed to determine their relation to ASH.
The aim of this study was to characterize HRR responses and to determine their relation to cardiac morphology and conventional risk factors for sudden cardiac death.
The goal of this study was to establish distinct patterns that reflect a rectal tumors' immune-phenotype and to determine their relation to patient outcome.
A number of related vascular risk factors and conditions -- for example, hypertension, diabetes, heart disease, and stroke -- have been studied to determine their relation to AD and VaD.
Also, new biomarkers associated with brain dysfunction and cognitive impairment are still recognized and need to be studied to determine their relation with delirium.
The aim of this study was to determine tumour blood flow modifying effects of electrochemotherapy with cisplatin, its effects on tumour oxygenation and to determine their relation to antitumour effectiveness.
In light of the obesity epidemic, we aimed to characterize novel childhood adiposity trajectories from birth to age 14 years and to determine their relation to adolescent insulin resistance.
This study is aimed to assess the expression of selected group of cadherin-catenin; E-cadherin, N-cadherin, α-catenin and β-catenin in subset of primary CRC and determine their relation to different clinico-pathological factors and survival [ 2].
