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We conducted a systematic review of the literature to determine the methodological quality of published randomized controlled trials (RCTs).
The aim of this study was to determine the methodological quality of articles on therapeutic procedures published in CIRUGÍA ESPAÑOLA and to study its association with the publication year, center, and subject-matter.
We limited the search to the period between 2004 and 2006 because we wanted to determine the methodological and reporting quality of diagnostic studies following the publication and dissemination of QUADAS and STARD.
The tool was applied to determine the methodological quality of the studies included in this systematic review (Table II).
To determine the methodological quality of the studies, each was assessed independently by three reviewers (CYGN, AER, SMAAE).
An important next step would be to determine the methodological quality, i.e. risk of bias, nature of outcomes, etc., of the current body of RCTs.
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A task force for the EULAR standing committee for Clinical Trials determined the methodological and logistical approach required for the development of evidence based guidelines for treatment of knee OA.
A task force for the EULAR standing committee for clinical trials determined the methodological and logistical approach required for the development of evidence-based guidelines for treatment of knee osteoarthirits (OA).
Three reviewers determined the methodological quality of the studies (CYGN, AER, SMAAE).
7 8 The focus of PROMs work to date has been on refining treatment decision-making for individuals and determining the methodological approaches to implementation and analysis.
Reasons for exclusion of the 130 references are detailed in Additional file 4. Three reviewers independently determined the methodological quality of the 36 references, of whom the first reviewer (JGH) screened all reviews and two reviewers (ALF, RV) both performed selection on half of the total number of included reviews.
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