"determine the difference" is correct and usable in written English.
You could use it in situations where you are asking someone to compare two things and identify the distinctions between them. For example, "Please determine the difference between these two models of electronic device."
To our knowledge, neither of those nations have the sophisticated sensors that can determine the difference between a natural N.E.O.
Those pennies often determine the difference between profit and loss — and in years without subsidies, turbine shipments drop sharply.
The online automotive information service Edmunds.com has a calculator on its Web site that lets consumers determine the difference between the two.
The plaintiffs have developed a formula to determine the difference between what women were paid and what they should have been paid.
As bitrates climbed above 128 kbps, however, our guesses became increasingly haphazard; none of us could determine the difference between 320 kbps and lossless.
To detect chemical weapons, Captain Regalbuto said, attaining "the ability to determine the difference between legitimate cargo and illegitimate cargo" is of "monumental" importance.
Opposition figures have used corruption accusations to undermine rivals in the Socialist-led coalition government, making it hard to determine the difference between pure and murky motives.
How you'd determine the difference between a digital magazine and a digital newspaper, I'm not sure (something to do with digital staples?!).
Each material has a unique "seismic velocity," which helps determine the difference between rock and oil.
To determine the difference, the optimal sa is subtracted from the proposed one.
The presence of this newly advantageous allele might determine the difference between survival and extinction.
