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Four separate approaches for fitting the da/dt data to determine the derived constants C and m are evaluated.
We also sequenced two inbred lines from distantly related populations to determine the derived and ancestral allele for each polymorphism.
We again used C. sp. 23 as the outgroup to determine the derived and ancestral state of indel mutations in C. remanei.
To control for differential selective constraints on DNA fragments, we used C. sp. 23 as an outgroup to determine the derived and ancestral state of indel mutations in C. remanei.
To calculate the derived allele frequency of SNPs at silent sites, we first used the nucleotide state of the most closely related Daphnia species available for each locus to determine the derived state of SNPs with a congruent method.
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Fay and Wu's H test [18] was performed by determining the derived allele from comparisons with black grouse (Tetrao tetrix) sequences described by [4], and statistically significant deviations from the standard neutral model were investigated using coalescent simulations based on the observed population mutation rate.
We determined the derived and ancestral state for 48,374 of these sites using the UCSC genome alignments of D. melanogaster with D. simulans and with D. yakuba.
Capillary dysfunction is summarised in a single parameter, CTH, which we propose determines the derived effects on extraction of oxygen and glucose in various tissue types.
We have analyzed outcome data of a population of NSCLC patients that received these TKIs to determine the benefit derived and to define the clinical and molecular parameters that correlate with response.
The minimum P can be determined when the derived CRLBs reach their stable values.
Static adsorption isotherms were determined and the derived parameters used to guide the choice of ligand structure and adsorption conditions to achieve favorable IgG2 mAb binding under dynamic loading conditions.
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