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Also, none of the mentioned algorithms could be applied to determine tandem duplication and inversion breakpoints.
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The genomic characteristics shown here for A. carterae have to be demonstrated for a larger sample size of dinoflagellates, including representatives from many different lineages to determine if tandem gene arrangement and high copy number are present across the entire lineage.
First, we analyzed the adjacent genes to determine whether tandem duplication has taken place.
c Spearman's partial correlation coefficient ρp is computed by controlling for the other two genomic properties listed in a To determine whether tandem paralogs with specific functions tend to have a greater number of intervening CTCF-binding sites, we performed enrichment analyses in Gene Ontology (GO) terms.
Alleles were distinguished by the number of tandem repeats as determined by Tandem Repeat Finder (11 ) (Technical Appendix).
The N-terminal sequence and internal sequences of the purified taro α-galactosidase (α-Gal) were determined using tandem mass spectrometry.
Product peaks were collected and their identification determined by tandem mass spectrometry.
The D0A6 abundance of this pair, as determined using tandem MS, decreased in all samples except for intestine.
The relative changes in the abundance of two pairs of isobaric disaccharides was determined using tandem MS, following the rationale of previously developed methods [36], [37].
The percentage of D0S6 in the D2S0/D0S6 isomer pair decreased dramatically resulting from HSulf2 treatment, as determined using tandem mass spectrometry (Fig. 1C).
The amino acid sequence of this C-terminal trypsin peptide was determined by tandem mass spectrometry (MS/MS) analysis to be GTLEGGSAGSG (Figure 3B), in which GTLEGG matched the C-terminal sequence of the M protein, and SAGSG matched the C-extein sequence of the IC-L peptide, all as expected.
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