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For reasons of ethics and efficacy, investigations in humans to determine sensitization and allergic responses of IgE production to innocuous food proteins are not feasible.
(iii) Skin-prick testing (SPT) is offered to determine sensitization to common allergens (Egg white, milk, peanut, cat hair, pollen, house dust mite (DerP1), 10 mg Histamine and a negative control).
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Here, we determine whether sensitization similarly influences OP-induced airway hyperreactivity.
Diagnostic standards related to BALF IgE levels, in order to determine fungal sensitization, do not exist.
This timepoint was included to determine if sensitization and the first challenge caused any lasting inflammatory reaction in either group.
Most relevant is Mtb exposure; we used the QFN test to determine Mtb sensitization and repeated clinical screening of mothers and infants to exclude TB disease.
Frigerio et al. reported that patient history taking is appreciably less reliable than gold standard testing in determining metal sensitization; the sensitivity of patient history is 85.5% and the specificity is 83.5% [ 6].
We determined PRA sensitization ratio and the associated anti-HLA IgG antibody distribution of the patient group.
Accumulating evidence spotlight on RhoA/ROCK1 signalling as a critical regulator in determining Ca2+ sensitization of the vascular smooth muscle cells contractile machinery [ 10, 22, 30- 36].
A systematic study of the complexes of 41 ligands with Eu3+ and Tb3+ revealed that the energy of the ligand triplet excited state is crucial in determining the sensitization efficiency of an antenna and should be at least 1,850 cm−1 higher than the lowest excited state of the lanthanide ion [ 21].
The in vitro skin sensitization test was performed to determine the sensitizing potential by assessing the changes in CD54 and CD86 expression in THP-1 cells using flow cytometry after 24 h exposure to a test compound (Fig. 5).
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