In the present study we sought to determine mechanism of action β-glucans in humans by determining the response in human DCs.
The environmental exposure unit (EEU) is an instrument designed to determine onset of action of antiallergic treatment.
Metabolic studies would be required to determine mechanisms of action.
Transcriptomic profiling of potential lead compounds was then used to determine mechanism of action.
In contrast, mice display paracrine Hh signalling in several organs but the use of human xenografts to determine mode of action appears inappropriate as these are chimeras.
When determining mechanism of action of a drug, it is often useful to determine through which death pathway the cells are progressing.
The programmed instructions determine the set of actions that is to be accomplished automatically by the system.
To determine the sites of action of the PIKfyve/VAC14/FIG4 complex in neurons, we determined the localization of endogenous VAC14.
We also determine genotoxic action of this extract in vivo.
And B: using a more extensive tissue specific set of drivers to determine the site of action.
