Sentence examples for determine mutation from inspiring English sources

In routine cancer molecular pathology, various independent experiments are required to determine mutation and amplification status of clinically relevant genes.

Although we lack direct information about the ancestral state of LTR nucleotides to determine mutation directionality (C to T or vice versa?), we tried to infer it by exploiting the availability of LTR quadruplets provided by the 14 pairs of intact orthologous LTR retroelements that we identified.

We utilized cell lines with different MMR deficiencies (hMLH1−/−, hMSH6−/−, hMSH3−/−, and MMR-proficient) to determine mutation rates.

To determine mutation frequencies of the TGFBR2 and ACVR2 coding microsatellites in cells with different MMR backgrounds (Table S1), nonfluorescent cells containing either MR TGFBR2 OF, TGFBR2 OF, MR ACVR2 OF or ACVR2 OF were sorted and exponentially grown for 7 to 35 days.

However, for unknown reasons, de Steenwinkel et al. used only 1 high-density culture of 10 CFU of each strain to determine mutation frequency.

CADMA uses HRM analysis to determine mutation status, which can be performed in a closed tube format without the use of any labeled oligonucleotides.

To determine mutations in the SRY gene in two sisters with 46, XY karyotype.

The aim of the present study was to develop rapid molecular assays to determine mutations responsible for elevated minimal inhibitory concentrations (MICs) to fluoroquinolones, tetracyclines, aminocyclitols, macrolides, lincosamides, phenicols and pleuromutilins in M. bovis.

Indicated are the neoplastic cell content of the samples (information provided by 6/7 labs), the type of tissue (biopsy or resection), origin of tumor tissue (primary or metastasis), if the tumor tissue was micro-dissected, the method previously used to determine mutation-status and for the samples in phase 3 the reason for inclusion.

To determine mutations that result in drug resistance, the Stanford University HIV Drug Resistance Database was utilized.

Co-variation analysis was performed to determine mutations or polymorphisms that were positively selected in association with TDR-associated mutations (Table  4).