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We also quantified DNA band intensities to determine linkages as unitless linkage values (ULVs) (see Methods).
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The results must be assessed statistically to determine linkage.
Transient outward K+current (Ito) and action potential duration (APD) were studied in 2-, 4-, 8-, and 9- to 12-month-old mice to determine linkage to ventricular remodeling (VR), ER, and heart failure (HF).
For association mapping filtered sites within OsHKT genes were used to determine linkage disequilibrium (LD) by correlation between alleles at two loci in TASSEL 5.0 (Bradbury et al. 2007) software and significance of LD among SNPs was determined by Fisher's exact test.
The Haploview v.3.3 software [30] was used to generate haplotypes, perform haplotype association analysis, and to determine linkage disequilibrium (LD) measures (r2) between the polymorphisms.
As with previous linkage assessments in observational studies [35], our protocol (Figure 1 and Table 4) included an evaluation of sequence data from env and gag for monophyly in maximum likelihood trees to determine linkage.
Occasionally, insufficient linkage or failure to determine linkage phase with default settings required relaxation of thresholds.
RECORD [ 51] was used to determine linkage groups and the order of markers within linkage groups.
The Bayes factor [ 27], or L-score, was computed to determine linkage as follows.
To determine linkage, mapping was performed in meiotic progeny from a cross to CC-1952 (Gross et al. 1988).
25 Record linkage on a large scale should involve a system of manual review in order to determine linkage quality, which involves checking patient identifiers.
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