phoP is a transcription regulator, therefore its mutation determines lack of expression of several genes, including virulence factors, such as ESAT6 [ 82].
A 93-bp deletion from the Y. pestis glpD gene encoding the glycerol-3-phosphate dehydrogenase determines lack of glycerol fermentation of the Orientalis biotype (8, 9 ).
54 Our understanding instead is that individual outcome reflects the interindividual heterogeneity of responses that can be potentially determined; lack of knowledge could be amended by a better understanding of individual responses.
Third, indigenous ethnicity is an important factor in determining lack of trust in foresters, implying that this barrier to trust must be overcome for higher levels of vertical integration to be achieved.
Therefore, we performed UNC5C IHC on the clinical specimens to examine the two-hit theory in which aberrant promoter methylation and allelic losses were the key factors determining lack of DCC.
This result suggests that the hybridization with the GFP tester population did not determine the lack of responses because of the expression of outbreeding depression; see also [ 31].
To determine whether lack of ASM activity affects synaptic membrane lipid composition, mass analysis of lipids was performed on synaptosomes of age-matched (7months) wild type (wt) and ASMko mice.
To further determine the lack of CD25 involvement in HSV-IL-2-induced demyelination, we used C57BL/6-IL-2rα−/ C57BL/6-IL-2rα−/ C57BL/6-IL-2rα−/5 in C57BL/6 mice using anti-CD25 mAb.
To determine if lack of Rgs2 affects cytokine production within these cells, we performed a protein cytokine array on the lysates of wild type and null MDSCs isolated directly from 3LL tumor tissue.
More research is needed to determine the lack of consistency.
