Sentence examples for determine its potency from inspiring English sources
With direct analysis of zebrafish embryos treated with a specific small molecule, it should be possible to determine its potency and specificity through phenotypic determination coupled with profiling a panel of representative kinases.
Together, the affinity and the efficacy of a drug determine its potency.
More work is needed on this approach to determine its potency.
We thus centrifuged SF from RA patients and used the resulting pellet to determine its potency on human neutrophils.
Enzymatic activity assays for native hTP in the presence of 5IUR were carried out in order to determine its potency as an inhibitor.
Thus, the molecular design of each C3-opsonin targeted complement inhibitor determines its potency in respect to the nature of the activator/surface providing potential functionality in PNH.
The purpose of the present study was to characterize the in vivo pharmacologic properties of Boc5, determining its potency and efficacy for antidiabetic and weight loss effects in both non-diabetic and diabetic/obese murine models.
To assess the mode of action of 1, we determined its potency against a TbUAP conditional null mutant (TbUAP-cKO) cell line in culture.
At present, we do not know the fate of the internalized mAb or how much of it targets to activated Ras as this may be a critical step determining its potency.
The number and type of chemical bonds a statin can establish with HMG-CoA reductase determines its potency and therefore determines its effects on cholesterol production. 2 Decreased production of cholesterol decreases the hepatic intracellular pool and subsequently provokes increased transcription of LDL receptors on the surface of hepatocytes.
There is only a partial understanding of how the properties of the materials used in the design of an antibacterial agent (core structures, functional groups) determine its biological activities: from inhibitory potency at the bacterial target to bacterial cell envelope permeation to human pharmacokinetics, all of which are complex and multifactorial.
