Exact(9)
To rule out possible embryonic toxicity and better determine base editing efficacy, HF2-BE2 mRNA was injected alone or together with gRNA-1 or gRNA-2.
However, they did not determine base excess subsets.
Siggaard-Andersen developed a nomogram [ 9] to determine base excess in the clinical setting.
The pyroluminescence intensity for each bead-containing well was used to determine base calls for each nucleotide incorporation step.
Although the probe hybridization method requires no direct sequencing, it requires several probes to accurately determine base changes.
We took advantage of Pacific Biosciences' (PacBio) single molecule [ 42], real-time (SMRT) sequencing technology's capability to determine base modifications during sequencing to identify putative methylation sites across both genomes, and identified that both genomes had adenine methylated exclusively.
Similar(51)
There, you must determine, based on mood and skin tone, what's right for you.
Briefly, blood was first collected 3 days before injections started to determine base-line values.
The gold standard Sequenom EpiTYPER system was used to determine base-specific cytosine methylation levels (11).
Note that a range for sensitivity analysis derived from 95% CI of each parameter distribution except * that based on assumption For each parameter we determine base-case values.
z-scores were determined based on FPKM.
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