Sentence examples for determine accessibility from inspiring English sources

Therefore, the different nucleosome distributions in our three cell types could not explain the FAIRE patterns, confounding views that nucleosome patterns per se determine accessibility.

These parameters were used to determine accessibility of enzymes depending upon their action pattern and directly affect the hydrolysis process.

One-third of Kenyan policy makers and program implementers and one-half of the Rwandan counterparts pointed out that the cost of an LAI would largely determine accessibility.

In the present study, we focused on TM10 of OATP1B1 and performed cysteine scanning mutagenesis to determine accessibility and potential involvement of individual amino acid positions in the substrate binding site/translocation pathway.

In several tree-nesting colonial avian species, tree height was identified as an important predictor of reproductive success and was suggested to determine accessibility of nests to ground and tree-dwelling predators (Post 1990; Childress and Bennun 2000).

In this study, we used cysteine scanning mutagenesis of TM10 in OATP1B1 to determine accessibility and potential involvement of the mutated amino acid residues in the substrate binding site/translocation pathway.

Our data show cell-type-specific patterns of DNA and histone modifications provide a modulatory layer by determining accessibility of genes to regulation by TGF-β/SMAD3.

Selection of adequate sub-molecular target epitopes determines accessibility for anchoring of drug conjugates and bulkier drug carriers, as well as proper signaling for uptake within the cell.

The challenge is that data backup and recovery is a costly process [ 144 ] and requires acute focus on data selecting, mapping, testing and determining accessibility roles in case of recovery process.

The chromatin structure surrounding the transcription start site, determined by the distance between individual nucleosomes comprised of DNA wrapped around histone octamers, is determined by both DNA methylation and histone modifications and determines accessibility of the DNA for transcription factors.

The chromatin structure can be modified through covalent modification to either the DNA or the histones, which in turn determines accessibility and recruitment of transcription factors and RNA polymerase II to the DNA.