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This suggested that contraction of D4Z4 repeats could determine a loss of Polycomb silencing in FSHD.
In general, PRPS1 gain-of-function mutations determine a loss of feedback regulation and hence enzyme superactivity, which in turn causes excessive uric acid production and gout.
These small differences can determine a loss of income to wasted overdraft fees.
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Quantitative PCR determined a loss of over 90% of nvp63 mRNA molecules after 48 h of siRNA incubation (Fig. 8D).
HFE variants affect TF binding, determining a loss of HFE-repressor function for TF uptake, thereby increasing iron transport within the cells.
To determine the average amount of value lost, housing researchers relied on sales data involving homes in the greater Chicago area to determine a typical loss in value due to a foreclosure.
To determine a natural weight loss for breastfed, exclusive, and nonexclusive newborns that are not exposed to common medical interventions in a hospital setting.
A meta-analysis could determine a reduced blood loss [ 15].
In other areas of law where there is guilt or innocence or a large money judgment, it is easier to determine a win or a loss.
There must be some way to determine whether a loss has occurred and how great that loss is.
One objective of the present work was to determine whether a loss of Unc-5C function contributed to subtilisin-induced LTD by using Unc-5C antibodies in combination with the pore-forming agents Triton X-100 (0.005%) or streptolysin O in rat hippocampal slices.
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