Furthermore, for the same determinations, and with the exception of pp65 antigenemia positive predictive value, the refinement introduced into pp65 antigenemia and CMV monitor by the inclusion of cut-off values did not significantly improve the respective negative and positive predictive values relative to raw pp67 mRNA determinations (table 4).
Lastly, Marks ordered Newport-Mesa to "un-redact the credibility determinations of the investigator" with the exception of employee identities and the dates of interviews.
The results were in accordance (<5-fold difference) with the original potency determinations with one exception (compound 2, 15-fold increase).
Systolic pressures of rats were determined in an interval of 15 min, with the exception that an additional determination was performed at 7.5 min after intravenous (i.v).v
Systolic pressures of rats were determined in an interval of 15 min, with the exception that an additional determination was performed at 7.5 min after i.v. injection of cromakalim to avoid losing effective values.
The assay was then conducted similar to the MIC determination above, using the spectrophotometric assay, with the exception that only MRSA isolate 0791 was used.
An identical protocol was followed for the determination of vitamin C (ascorbate plus dehydroascorbate), with the exception that the samples underwent a reduction step with Tris (2-carboxylethyl) phosphine (TCEP) (Molecular Probes, Eugene, Oregon, USA).
In the studies in which it was specified, death determination was based only on circulatory criteria, with the exception of the two French studies [ 18, 27] in which an additional neurologic screening was performed according to legal requirements.
With the exception of one outlier, S determinations by HR ICP-MS and SO42- by ion chromatography were essentially identical [see Additional file 2, Fig S1].
