Not only do they permit decisions based on little more than judicial hunches about "reasonable investor" behavior, the argument goes, but they also conflict with Supreme Court precedent teaching that materiality determinations are highly fact-intensive and thus should rarely be made before trial.
However, structural determinations are highly recommended to understand conformational effects and to use the BC-construct for rational design studies to produce novel multifunctional biocatalysts.
Sample size determinations are highly sensitive to changes in design assumptions, which behoves sponsors to be rigorous when estimating these variables.
It is no surprise that many teachers have an interest in neuroscience and psychology since areas such as memory, motivation, curiosity, intelligence and determination are highly important in education.
Ascorbic acid is a chemical substance with significant role in human and its determination is highly desirable for analytical and diagnostic applications.
Typical electropherograms representing different haplotype combinations are shown in Fig. 2. Allele length determination was highly reproducible (Table 3).
Taken together, these results suggest that organ identity and cell fate determination are highly regulated by the temporal and spatial expression of genes.
Traditionally, the principle of autonomy as the right of self-determination is highly respected in the practice of clinical genetics, by which is meant the right of free choice and control of patients.
These authors found good agreement with conventional offline analysis of MFI (mean difference of −0.031, SD = 0.198 (95 % CI −0.43, 0.37)), and MFI bedside determination was highly sensitive (94 %) and specific (92 %) for detecting impaired microvascular flow.
