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ETC determinations of skin fibroblasts were done at CIDEM [23] or Mayo Laboratories.
In addition to determinations of skin plus SAT thickness described above, an estimate of general adiposity was also made from the CT data.
Product tolerance was assessed via clinical erythema and dryness grading, subject self-assessment, and determinations of skin barrier integrity (transepidermal water loss) and stratum corneum protein changes.
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Determination of skin permeation using the Franz cell setup -- 13.3.4.
Determination of skin penetration using the Franz cell setup -- 13.3.3.
After each application, determination of skin parameters was performed within 30 minutes.
Gata3 is involved in the determination of skin cell lineages and when it is conditionally knocked down in the epidermis and hair follicles the animals suffer growth defects and dwarfism [26].
KIT and OCA2 genes are both mainly known to be involved in the determination of skin colour [ 24].
The movement of the skin in and out the probe is illustrated in a pressure deflexion curve, which allows the determination of skin stiffness and viscosity parameters.
GATA3 has been recently shown to be involved in the development of hair follicles and in the determination of skin cell lineage in mice [ 14, 18].
Of note, variants of MCR1 are important in the determination of skin types, hair color, response to tanning and propensity to develop melanoma., One HRE site was found to be located at the -248 position and two HREs were found to be located at the +209 and +383 positions of POMC gene.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com