The present paper addresses this point using a recently reported new method for the determination of selectivity that can be implemented directly on porous electrodes, without using rotating disc or ring disc electrodes.
Different methods are available for determination of selectivity of an ISE.
For determination of selectivity, the affinity of both reference substances was assessed on human DAT and SERT membranes and revealed >10 μM for both compounds for DAT and 409 ± 43 nM (Me@HAPTHI) and 10,274 ± 1207 nM (HAPTHI) towards SERT, respectively, (n ≥ 5 triplicates).
Method validation included the determination of selectivity, linearity, specificity, repeatability, the limit of detection, limit of quantification, decision limit (CC α ), detection capability (CC β ), and recovery.
Method validation included the determination of selectivity, linearity, specificity, reproducibility, recovery, the decision limit (CC α), detection capability (CC β), limit of detection (LOD), and limit of quantification (LO Q.
Grimm, C., Vierock, J., Hegemann, P. & Wietek, J. Whole-cell patch-clamp recordings for electrophysiological determination of ion selectivity in Channelrhodopsins.
These differences in surface speciation and their probable roles in the determination of product selectivity are discussed.
Such assemblies can be intriguing templates for building novel molecular architectures, and be employed as a combinatorial tool for quick determination of interaction selectivity for nanoparticles.
Our data revealed that YnaIMet158 in the transmembrane pore was instrumental in determination of ion selectivity.
Current research is directed towards determination of molecular selectivity and sensitivity limits at which Raman scattering from the tested molecules can be enhanced by graphene [10].
