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In this review, we propose a coherent, interoperable platform comprising knowledge engineering and hypothesis generation components for rapidly making determinations of confidence in mechanism and safety (among other goals) using experimental data and expert knowledge.
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The determination of confidence intervals through a bias-reducing bootstrap estimator is investigated.
Inference, i.e., determination of confidence and prediction intervals, is proposed as complementary criteria.
Taguchi approach for predicting the mean response characteristics and determination of confidence intervals for the predicted mean has been applied.
Processing experimental data obtained and the determination of confidence intervals for 95% confidence probability were conducted with the mathematical statistics methods by means of software application of origin.
There are two main objectives for the determination of confidence limits for animal disease monitoring results.
Functions for processing raw mass spectrum data and the determination of confidence intervals are also included.
The sampling problem requires the determination of confidence intervals on ℳ with respect to the size of SV being examined.
Identifiability analysis and determination of confidence intervals reveal that the model allows reliable predictions regarding the dynamics of PP2A deactivation and IKKβ phosphorylation.
Cross-validation based determination of confidence levels of the included model reactions (Additional file 1: Table S7) show high or moderate confidence for approx. 80%% of the reactions, indicating that only approx. 20 % of the reactions did not have expression based support, i.e. were added by FASTCORMICS to generate a consistent network model.
The tools used in this work to perform numerical integration of coupled ODEs have not permitted the determination of confidence limits for the k2, k3 and k4 constants of the kinetic scheme, and also the sparseness of rate constant data points leads in some instances to high confidence limits for activation energies.
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Justyna Jupowicz-Kozak
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