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One of the most challenging determinations in evaluating mechanistic data is whether an identified MOA is the cause of cancer (or another adverse health outcome).
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The results showed an excellent agreement of the protection rate in both assays (Fig. 5), suggesting the improved microtiter neutralization assay is as sensitive and reliable as p24 antigen determination in evaluating HIV-1 NAbs from sera or plasma.
"If, based on the information available at the time of the determination, there is a rational basis for the determination, the department will not substitute its judgment for that of the educational agency or institution in evaluating the circumstances and making its determination," the proposed regulations said.
A growing body of information suggests that determination of AST isoenzymes in human serum is useful in evaluating damage to some of these organs [18].
All the determinations were evaluated in duplicate following best practice in clinical analysis.
Thus, to validate this platform, all intermediate steps from phage quantification to sequence determination were evaluated in a direct, simultaneous (i.e., side-by-side) comparison with the conventional methodology.
The results of every determination were evaluated in relation to the corresponding control culture.
In this study, the performance of five feasible methods for microalgal biomass determinations was evaluated and compared.
Our follow-up strategy implied that all patients, who harbored the JAK2V617F mutation upon initial determination, were re-evaluated in the beginning of 2009.
AB and CRH conceived the study and designed the experiments, AB performed the experiments, TZ advised in microscopic FRET determination and evaluated the data, AB and CRH wrote the paper.
Stage determination was evaluated by measuring body weight gain, trypanosome counts in the blood and CSF, and trypanosome immunostaining in the brain (from D0 to D22 post-infection).
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