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The influence of blood content on MNP determination was measured by mixed mouse blood and MNPs.
Each lipid determination was measured in triplicate.
The proportion of explained variance (coefficient of determination) was measured by R. We selected 29 candidate genes in the warfarin interactive pathways (Fig. 1 and Supplementary Table S1) and tested them for ∼800 SNPs that comprehensively captured common variation based on measures of LD (r ≥ 0.8).
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The two-phase pressure drop and the liquid hold-up (liquid RTD determination) were measured for pressures up to 8.1 MPa.
Three-bond homonuclear coupling constants (JHH) used for structure determination were measured from H-1D spectra recorded at 900 MHz (16 384 complex points, dwell-time 92.5 μs) on both D2O and H2O samples.
Duplicate determinations were measured for each paw and averaged.
Protein determinations were measured with SOFTmax software package on an E-max microplate reader (Molecular Devices, Sunnyvale, CA).
For biomass determination OD580 was measured and divided by a OD580/biomass correlation factor of 3.25 OD580/(g L−1).
Within 20 minutes before TSB determination, TcB was measured on the infant's forehead, protected from direct sunlight and avoiding areas with hair, bruises, nevi or other skin anomalies.
Coefficient of determination (y axis) was measured for different values of the number of modules (x axis).
Analytical determinations Plasma glucose was measured using the glucose oxidase method (Beckman Instruments, Fullerton, CA, USA).
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