Exact(4)
Most standard NOE-based structure determination protocols apply the available distance restraints on to a single conformation.
An important and general method to compare different structure determination protocols is to generate synthetic data and use this as input to the different protocols.
For example, the idea of using reference ensembles to validate structure determination protocols has recently been applied to non-native states of proteins [76], [77] as well as revisiting ensemble refinement against Xray diffraction data [8].
The good agreement with predicted distances illustrates the potential of the label for implementation into 3D solution structure determination protocols for RNA and RNA RNA or RNA protein complexes.
Similar(4)
The objective of this study was to develop a simple and accurate PCR-based sex determination protocol, which can be applicable to cattle, sheep and goat meat.
The synthetic data were subsequently used as input to a structure determination protocol.
These cells were also cultured using the retinal determination protocol and analyzed for expression of the EFTFs at the end of two weeks.
The similarity of iPS cells to hES cells led us to ask whether these cells would respond to our retinal determination protocol like the ES cells.
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