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Sufficient ENM characterization can help minimize overestimations of ENM toxicity and incorrect determination of toxicity mechanisms from the unacknowledged presence of toxic impurities (e.g., metals, organic compounds, and endotoxins).
The obtained supernatant was used for the determination of toxicity on RBCs at 540 nm [23].
We thank K. Wedig (municipal wastewater treatment plant of Greifswald, Germany) for support during determination of toxicity using Vibrio fischeri.
In their study, it was found that there is a linear and direct relationship between the bacterial enzymatic activity and colony count in determination of toxicity.
However, individual elements, e.g. determination of toxicity via mechanistic studies, use of genomics or integration of QSAR elements, have been explored for some time now and, in individual cases, have already been applied over the last 10 years.
This research demonstrated that the combination of bioassays and chemical analysis provided a more accurate determination of toxicity in these complex environmental mixtures.
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The primary end point of this phase II study was response rate and secondary end points included time to progression (TTP), survival and determination of toxicities.
For the determination of possible toxicity of the aqueous extract, acute toxicity test was performed.
Determination of acute toxicity is necessary to evaluate the toxic effects after oral administration of a single dose of the drug.
The determination of acute toxicity in athymic nudes mice proved some compounds to be non-toxic, making them good candidates for further study as antitumor agents.
His published work includes contributions on the estimation of strophanthus, thyroid preparations and on the determination of the toxicity of neoarsphen-amine.
More suggestions(13)
determination of impairment
determination of dose
determination of classification
determination of hazard
determination of harm
determination of effect
determination of consequences
determination of effects
determination of toxicant
determination of acute
measurements of toxicity
estimation of toxicity
determination of toxicological
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