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Moreover, determination of the structures significantly extended our understanding of structure variability within the Picornavirus family.
On the other hand was the determination of the structures of the new types of compounds which were being synthesised.
We report direct determination of the structures and dynamics of interfacial water on a hydrophilic surface with atomic-scale resolution using ultrafast electron crystallography.
One of the first challenges has been the determination of the structures of proteins encoded by the individual genes.
On the one hand was the type of work I was involved with at Imperial College – the determination of the structures of organic natural products [2].
Among these, X-ray crystallography has recently enabled determination of the structures of several large and complex RNAs, as well as of ribonucleoprotein complexes.
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Therefore, in general, folding algorithms are used for the prediction of the structure corresponding to the consensus sequence, whereas experimental structural techniques can be applied to the determination of the structure corresponding to the most abundant sequence in the population.
He was awarded the prize in 1958 for his determination of the structure of the insulin molecule.
The traditional method, used for example in the determination of the structure of DNA, is to produce a crystal form of the substance to be studied, then blast it with x-rays.
Modern conclusive knowledge of the structures of heteropoly compounds did not begin until 1934, with J.F. Keggin's determination of the structure of H3 [PO4W12O36]∙5H2O by the most direct means, X-ray diffraction.
At the Cavendish Laboratory at the University of Cambridge, where Sir Lawrence was professor, J.D. Bernal was studying the use of X-ray diffraction for the determination of the structure of large biological molecules.
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