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Key issues in early clinical trials of targeted agents include the determination of target inhibition, rational patient selection based on pre-treatment tumour characteristics, and assessment of tumour response in the absence of actual shrinkage.
Determination of target regimes is a multi-parameter global optimisation problem.
Finally, the proposed strategy was used for determination of target PAHs in real water samples (tap and hookah waters).
The proposed method is applied to the determination of target analytes in milk samples from local markets.
It was also successfully applied to the determination of target miRNA spiked into human total RNA samples.
A sandwich-type immunoassay format was adopted for the simultaneous determination of target biomarkers in a low-binding microtiter plate.
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The optimized method was applied for the determination of targets in surface water samples.
One of the things that has changed is that the national determination of targets has created the necessary domestic conversations with stakeholders.
In contrast to the 3′ terminal variations, the 5′ terminal variations are predicted to have more impact on the determination of targets [ 41, 59].
Although the microarrays are designed with tiles for specific pathogen targets [ 29, 30, 32], they are capable of detection and correct sequence determination of targets differing by up to 15% from the sequence present on the microarray.
A correction is needed in order to transform these confidence levels to ones which are appropriate to determination of targets from the full genome, in which the number of negatives can outnumber the number of positives by a large factor.
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willingness of target
setting of target
quantification of target
characterization of target
establishment of target
design of target
persistence of target
determination of objectives
rules of target
determination of targets
determination of gender
determination of support
determination of boundary
determination of registration
determination of rock
determination of love
determination of rescue
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