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The validation results demonstrated that the developed method was suitable for the quantitative determination of potential impurities in agomelatine.
Determination of potential drug toxicity and side effect in early stages of drug development is important in reducing the cost and time of drug discovery.
This paper deals with the numerical determination of potential and current distribution along the reinforcement when using patch repair applied to reinforced concrete elements.
These data allow determination of potential immunological responses that could mediate pathology observed with mutant forms of amyloid beta, as well as lead to the generation of safer vaccine preparations.
Results for the determination of potential antioxidant properties of the synthesized compounds showed that compounds 5d and 5e containing pyrazino[1,2-a]indol-1-one backbone were the most acive and even comparable to Trolox.
The identification of altered gene expression profiles with microarrays is best viewed as the first step in the determination of potential disease-associated genes; however, the false-positive rate can be high, particularly with small sample sets and in view of the typically small differences observed in brain expression studies.
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A new apparatus for determination of potentials of zero charge by the immersion method is described.
The focus on element-at-risk, common to earlier BAER determinations of potential debris flow risk, proved difficult to accomplish quickly and left the possibility of overlooking locations with significant risk during evaluation of areas burned by large fires.
Determined apparent bimolecular rate constants together with determination of reduction potential and nucleophilicity of the selected compounds allowed us to propose a mechanism of inhibition.
Our results allow a qualitative determination of the potential release of ENMs into technical or environmental compartments, with the highest potential release expected during recycling.
Brown, M. A. et al. Determination of surface potential and electrical double-layer structure at the aqueous electrolyte-nanoparticle interface.
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