If you're a people manager, you might look around at the bustling activity of your team and the looks of intense determination on their faces and assume that everyone understands how their work contributes to the company's bottom line.
Everything I gained from that, it's not something that I realized that I really had, but it's the sort of intense focus, the determination, the fire and desire that pushes you to do things that are difficult, and to want to do it even more when it gets harder.
Just as no one builds a multi-billion dollar empire without some sort of savage determination and intense will to power (otherwise they would have stopped at some earlier point, taken their winnings and gone home), no one accumulates power and then declines to use it in the face of existential threats—of which Thiel counted Gawkeras one to his business interests.
Because miRNAs exert these functions primarily through the repression of target genes, the determination of miRNA targets has been an area of intense research.
That point of intense exertion, where it takes every ounce of determination to fight through the fatigue, that's probably the only time I ever think of just one thing.
There have been suggestions that the development of an X-ray free electron laser could revolutionize the determination of protein structures, by using an intense but ultra-short light pulse to obtain data (Neutze et al., 2004).
Despite years of intense research aimed at discovering the molecular basis for spider silk mechanics, determination of full-length spidroin sequences has rarely been achieved [ 11, 12].
Despite decades of intense physiological and biophysical research, eukaryotic Nav channels have so far eluded high-resolution structure determination because of their biochemical complexity.
Only two random numbers are needed per iteration in this routine, but the determination of which event will occur is more computationally intense as well as determining the total rate, since the table of events is longer.
