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The test for the determination of HPV has recently been included in the screening programmes and, since 2006, 213 HPV positive cases have been detected in the study area.
Another critical feature of the HPVDetector is determination of HPV integration sites at the host genome.
These findings are bolstered by an external quality control mechanism for the determination of HPV DNA in the study population that included a determination of HPV blind to knowledge of gender and of the HPV results of the corresponding partner.
Determination of HPV status was carried out according to methods described in detail elsewhere (Allen et al, 2000).
Therefore, determination of HPV status in esophageal cancer may also be helpful in predicting the treatment outcome.
Therefore, there is the need for easy, safe, non-invasive sampling methods for the determination of HPV infection and of the immune responses to HPV.
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At the local laboratory serum aliquots for the determination of HPV-16 and HPV-18 antibodies by ELISA were obtained and frozen immediately.
Therefore, determination of the HPV genotypes alone may not be sufficient in assessing the progression of cancer in uterine cervix.
Accordingly, determination of type-specific HPV prevalence in a region is considered to be one of the important steps towards cervical cancer prevention.
In summary, a more accurate RCA-seq superior to PCR cloning and sequencing has been developed in our lab for HPV genotyping and determination of SNPs in clinical HPV variants.
The elucidation of these signal transduction systems and, more importantly, their interrelations in the early stages of the HPV-dependent transformation processes could provide indications for novel therapeutic strategies and/or a potential marker test for the clinical determination of pre-cancer, HPV-transformed cells in the cervix.
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