Sentence examples for determination of efficacy from inspiring English sources
Objective: Determination of efficacy in presence of bleeding of CDS, a collagen/membrane fleece composite, in a rabbit uterine horn simple abrasion model.
The proposed Phase 2 design allows for preliminary determination of efficacy that may be restricted to a particular sub-population defined by biomarker status (presence/absence).
Once drug candidates are identified, novel clinical trial designs and selection of appropriate outcome assessments will be needed to enable definition and evaluation of the appropriate dose and dosing regimen and determination of efficacy.
Multiregimen drug testing, paired with next-generation sequencing before and after therapy and timed tumor pharmacodynamics enables determination of efficacy, signaling pathway alterations, and mechanisms of sensitivity-resistance in individual models.
According to these results, the fluorescence lifetime should be considered as a patient friendly approach for fast evaluation of tumors with mid- to high-level expression of HER2 receptors, using only one measurement in diagnostics and determination of efficacy of treatment intervention.
Different models, ranging from test tube experiments to cell cultures, animals, healthy human subjects, and even small numbers of patients that are involved in clinical trials, are used at different stages of drug discovery and development for determination of efficacy and safety.
On the other hand, hybrid designs are intended to permit determinations of efficacy using different endpoints in different strata for example, direct superiority to placebo in one stratum and non-inferiority to an active control in a different stratum.
Patients who were not evaluable were regarded as failures (non-responders) for the purpose of efficacy determination.
These findings will have important implications for HIV-1 vaccine design and determination of vaccine efficacy.
A fuller understanding of the mechanism of vaccine action including determination of the efficacy and duration under varying conditions of malaria transmission will be reached through the conduct of properly designed Phase III trials.
