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Our results show that H2O2 induced over-activation of the canonical WNT pathway, indicating: (1) that free radicals in oxidative stress and subsequent lipid peroxidation are initial causative factors for activation of the canonical WNT pathway; and (2) the possible involvement of HNE in oxidative stress-mediated signalling.
Identification of causative factors for common, chronic disorders is a major focus of current human health science research.
Umbilical cord abnormalities are considered as one of the causative factor for birth asphyxia.
The NTSB looks at three broad potential categories of causative factors to make its determinations: user, equipment, and conditions.
In addition, the application of epiMiner on a real Age-related Macular Degeneration (AMD) data set provides several new clues for the exploration of causative factors of AMD.
We hope that, from these results, some clues could be provided for the exploration of causative factors of AMD.
In addition, accumulation of bile acids is a causative factor for jaundiced heart [ 5].
Unlike periprosthetic fractures of the tibia, malalignment has not been shown to be a causative factor for periprosthetic fracture of the femur [6].
Deregulation of this process is a major causative factor for many diseases.
Some reports suggest that a functional disturbance of microvessels itself can be a causative factor for microthrombi.
Focal disturbance of the hepatic blood supply has been advocated as the most likely causative factor for the concomitant development of these benign hepatic lesions.
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