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The present method was also applied for the determination of caffeine in cola drinks and simultaneous determination of caffeine and PA in pharmaceutical formulations.
Tanaka E. Simultaneous determination of caffeine and its primary demethylated metabolites in human plasma by high-performance liquid chromatography.
Further, it was successively used for the selective and simultaneous determination of caffeine in the presence of PA.
The present monolithic MIP column was successfully applied for the quantitative determination of caffeine and theophylline in different kinds of green tea.
A rapid method based on dynamic microwave-assisted extraction (DMAE) coupled on-line with clean-up was developed for the determination of caffeine in tea samples.
This article reports the electrochemical determination of caffeine in the presence of paracetamol (PA) using a self-assembled monolayer (SAM) of non-peripheral amine substituted copper II) phthalocyanine (4α-CuIITAPc) on glassy carbon electrode (GCE).
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Caffeine competitively inhibits ALP enzyme and the determination method of caffeine by the biosensor was based on this inhibition effect of caffeine.
Dimitrovska et al. [ 23] described the conditions for the determination of propyphenazone, acetaminophen, caffeine, and codeine phosphate in commercial tablet dosage with preparative thin layer chromatography.
The UV/Vis spectrophotometric methods have been reported by many researchers as preferred method of caffeine determination because of its relatively low cost, rapidity, high accuracy and reproducibility.
NIR spectrophotometry can also be used as alternative choice of caffeine determination using reduced amount of organic solvent (dimethylformamide) and univariate calibration technique.
Therefore, the maximum error that might occur in the determination of lowest amount of caffeine (0.5% w/w) in green coffee beans containing maximum amount of theobromine (0.01% w/w) will be 2% which is within the acceptable range.
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