Sentence examples for determination network from inspiring English sources
Having established that orthologs of many regulatory genes involved in anterior neural specification are also expressed within the anterior ectoderm of sea star embryos, we sought to determine if orthologs of transcription factors involved within the retinal determination network are also expressed within echinoderm embryos.
Duplication appears to underlie recruitment of Sxl to the Drosophila sex determination network [ 45].
Perhaps the functional relationship between these gene pairs is more constrained than that of other genes in the retinal determination network.
The result was a significant upstream reorganization of the yeast sex determination network without the need for any parallel changes to the downstream output of the network.
These important structural changes in the protein provide further evidence for the relaxation of purifying selection on tra coinciding with the recruitment of Sxl in the sex determination network.
Because sex-biased expression, and perhaps alternative splicing, is expected to be regulated by the canonical sex determination pathway, we addressed the level of control of tango13 within the sex determination network by examining its splicing via qPCR in XX females, XX pseudomales, and XY males.
Our results show under what conditions network mutations causing differential regulation can lead to the reshaping of sex determination networks.
Comparative study shows that sex determination networks evolve by recruitment of novel regulators higher up the pathway [ 17].
Sex determination networks evolve rapidly and have been studied intensely across many species, particularly in insects, thus presenting good models to study the evolutionary plasticity of gene networks.
The ability of cooperative transcription factors to facilitate adaptation also has empirical support, from observations in the sex determination networks of different yeast species [ 7- 9].
To address this issue we consider sex determination networks, as they evolve rapidly and are well characterized in species at varying phylogenetic distances, for example insects [ 12, 13], worms [ 14], fishes [ 15] and mammals [ 16].
